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Qualifying Therapeutic Discovery Project Grants for the State of Texas

The listings below represent the applicants that have been awarded a Qualifying Therapeutic Discovery Program Grant.

The project descriptions below were extracted from the applicant certification forms as submitted.

Texas $ 34,166,951.65
Applicant Name Project Name Grants Awarded for 2009 Grants Awarded for 2010
Access Pharmaceutcals Inc Tumor targeted docetaxel nanoparticle $ 65,000.00 $ 179,479.24
Access Pharmaceuticals inc Colalamin Insulin Oral drug delivery $ 216,000.00 $ 28,479.24
Access Pharmaceuticals Inc Mucoadhesive Liquid Drug Delivery   $ 168,750.00
Access Pharmaceuticals Inc Cobalamin siRNA Delivery Vehicle   $ 244,479.24
Access Pharmaceuticals, Inc ProLindac $ 244,479.24  
Access Pharmaceuticals, Inc Thiarabine for the treatment of hematologic cancers $ 15,000.00 $ 229,479.24
Access Pharmaceuticals, Inc Polymer-Based Platinum (IV) Prodrugs   $ 87,500.00
Agennix, Inc TALACTOFERRIN $ 244,479.25  
AKELA PHARMA USA INC FENTANYL TAIFUN® AS A RAPID-ACTING INHALED OPIOID ANALGESIC FOR TREATING CANCER PAIN $ 244,479.25  
Albumetrix, Inc EPR Spectrometer for Sepsis and Cancer Diagnostics $ 244,479.25  
America Stem Cell Inc Engraftin $ 244,479.25  
Aperion Biologics, Inc Humanization and Rational Engineering of Xenograft Tissues for Regenerative Medicine $ 244,479.25  
APOCELL INC DEP Technology   $ 244,479.25
Apollo Endosurgery Inc Overstitch TM Endoscopic Suturing System $ 244,479.25  
Apollo Endosurgery Inc. SuMO Submucosal Operation $ 244,479.25  
Applied Nanotech Inc Breath analysis for identification of lung cancer $ 81,893.30 $ 78,942.24
AROG Pharmaceuticals Development of Novel Anticancer Drug, PDGFR Inhibitor, CP-868, 596 for Treatment of GIST   $ 244,479.24
AROG Pharmaceuticals LLC Development of Novel Anticancer Drug, PDGFR Inhibitor, CP-868,596 for Pediatric Gliomas   $ 244,479.24
AROG Pharmaceuticals LLC Development of Novel Anticancer Drug, PDGFR Inhibitor, CP-868, 596 for Adult Gliomas   $ 244,479.24
AROG Pharmaceuticals LLC Development of Enteric-Coated Tablet Formulation for Novel Anti-Cancer Drug, CP-868,596   $ 95,850.00
Articulate Labs Inc Improving Neuromuscular Electrical Stimulation for Ambulatory Osteoarthtitic Knee Treatment $ 4,308.37 $ 2,347.06
Assurance Biosciences, Inc. Salivary Breast Cancer Marker   $ 235,443.00
Asuragen Inc Comprehensive Test for Fragile X Syndrone $ 112,026.00 $ 28,376.00
Asuragen Inc. Comprehensive Molecular Diagnostic Assay for Thyroid Cancer $ 67,481.00 $ 176,998.25
Asuragen, Inc Assay for monitoring and early detection of pancreatic cancer $ 35,991.00 $ 188,136.50
Asuragen, Inc. Cystic Fibrosis Test for Detection of Genetic Mutations $ 10,518.50 $ 583.50
Asuragen, Inc. BCR/ABL1 Quant™ Test for Monitoring Treatment in Chronic Myeloid Leukemia $ 53,827.00 $ 190,652.25
Asuragen, Inc. Diagnostic Assays for Detection of Cancer in Biofluids $ 101,141.00 $ 71,369.00
Atumida, Inc. Transforming Clinical Outcomes for Hemorrhagic Shock And Vascular Ischemic Diseases $ 29,104.10 $ 51,221.67
AuricX Pharmaceuticals Inc Oral Vancomycin $ 128,739.10  
AZAYA THERAPEUTICS INC Clinical Development of Liposomal Formulation of Docetaxel (AT1-1123) $ 244,479.25  
Bellicum Pharmaceuticals, Inc Development of Therapeutic Vaccine BPX-101 for the Treatment of Prostate Cancer $ 244,479.24  
BiO2 Medical, Inc. Device for the prevention and treatment of Pulmonary Embolism in hospitalized patients $ 244,479.24  
Biomedical Development Corporation Evaluate Unique Antimicrobial Oral Rinse in a Human Trial of Chronic Oral Imflammation and Investigate its Effects on Biological Markers indicative of Systemic Diseases $ 22,550.53 $ 80,571.50
BioNumerik Pharmaceuticals, Inc Karenitecin Phase III Development Project $ 244,479.25  
BioNumerik Pharmaceuticals, Inc Tavocept Phase III Lung Cancer Project $ 244,479.25  
BIOO SCIENTIFIC CORPORATION BIOO-2010-018-Rriptrp $ 15,000.00 $ 25,000.00
BioTex, Inc. Rapid Microbial Identification by MALDI-TOF Mass Spectrometry of Ribosomal RNA $ 166,817.51 $ 77,661.73
BIOTHER Corporation Novel Cancer Vaccine Protein Therapeutic T1-IR for Skin, Breast and Pancreatic Tumors $ 10,000.00 $ 234,479.24
Blue Box Health Inc. Improvement of Survival, Rehospitalization Rates and Treatment Costs for Heart Failure Patie   $ 244,479.25
Castle Biosciences, Inc. Proprietary DecisionDx family of molecular diagnostic assays $ 122,741.50 $ 121,737.75
Clear Vascular, Inc. Diagnostic & Therapeutic Application of Tin-117m/Annexin $ 244,479.24  
Conductance Technologies, Inc Admittance for Heart Failure Detection   $ 19,250.00
Convergen LifeSciences, Inc. CNVN Nanoparticle Targeted Therapy for Cancer   $ 244,479.25
Cormedics Corporation PeriPort Delivery Device $ 94,317.50 $ 103,500.00
Difusion Technologies, Inc CleanFUZE antibiotic therapeutic delivery system $ 244,479.24  
DisperSol Technologies, LLC Novel drug formulation method based on thermokinetic mixing. $ 148,944.90 $ 95,534.35
DNAtrix, Inc. Tumor-specific adenovirus Delta24-RGD for malignant glioma   $ 65,752.50
DuoPhos, LLC Therapeutic control of dietary phosphorus absorption in CRF, ESRD, and hypertension $ 117,563.50 $ 126,915.74
Electrochemical Oxygen Concepts, Inc. TransCu 02 Project $ 230,664.00 $ 13,815.24
Ensysce Biosciences Inc. Therapeutic siRNA for the treatment of cancer with delivery using SWCNT $ 186,436.50 $ 58,042.74
Entrigue Surgical, Inc. Middle Turbinate Implant $ 164,784.00 $ 72,127.50
Entrigue Surgical, Inc. Sinus Dilation and Patency System $ 116,192.00 $ 128,287.25
EverHeart Systems Fully Implantable Left Ventricular Assist Device (LVAD) System $ 95,719.73 $ 56,414.03
Excel Diagnostics, Ltd. 177Lu-DOTATATE $ 33,330.00 $ 133,750.00
Fabre-Kramer Holdings Inc Gepirone-ER $ 244,479.25  
GenSpera, Inc G-115 Prodrug for teatment Of Prostate Cancer   $ 244,479.25
GenSpera, Inc G-202 Prodrug for Solid Tumor Cancers $ 244,479.25  
Gradalis Inc FANG Vaccine $ 244,479.24  
Gradalis inc bi-shRNA-1 lipopplex $ 160,052.17 $ 84,427.07
Gradalis, Inc (formerly known as Murex Pharmaceuticals, Inc Development of a bifunctional shRNAstathmin (bi-shRNASTMN1) $ 244,479.24  
Gradalis, Inc. GNE Lipoplex $ 146,480.82 $ 97,998.42
GreenVax, LLC Vaccine development for pandemic diseases $ 31,849.41 $ 212,629.84
Halsa Pharmaceuticals, Inc Zag as a therapeutic for the treatment of type 2 diabetes and obesity $ 244,479.25  
Incell Corp LLC Cell Manufacturing and Testing for personalized therapies $ 118,391.50 $ 126,087.75
Influmedix Inc Development of Drugs that Target the Influenza Virus M2 Proton Channel $ 244,479.25  
InGeneron, Inc. Autologous Cell Therapy for Myocardial Infarction at Point-of-Care $ 244,479.25  
Introgen Research Institute Inc Nanoparticle therapy for lung cancer $ 78,566.50 $ 100,000.00
Iso Therapeutics Group, LLC Liquid Brachytherapy-A Novel Treatment for Solid Inoperable Tumors $ 44,500.00 $ 188,500.00
IsoTherapeutics Group, LLC A Novel Therapeutic Radiopharmaceutical for the Treatment of Metastic Bone Cancer $ 22,500.00 $ 219,000.00
Joyian Pharmaceuticals Diazonamide Analogs: A new Class of Anti-mitotic Cancer Therapeutic without Overt Toxicity $ 244,479.25  
Joyian Pharmaceuticals, Inc. Smac Mimetics as Novel Anti-Cancer Therapy $ 244,479.25  
Keraplast Technologies, Ltd Intravaginally delivered functional keratin for the treatment of atrophic vaginitis.   $ 156,100.00
Keraplast Technologies, Ltd. Second Degree Burns Keratin Efficacy vs. Standard of Care Clinical Study Protocol, 2010-010   $ 244,479.25
LASER TISSUE WELDING,INC LASER TISSUE WELDING-PRE-CLINICAL RESEARCH $ 16,996.00 $ 227,483.25
LDR SPINE USA, INC MOBI-C CERVICAL DISC PROSTHESIS $ 244,479.24  
Lynntech Inc An Improved Diagnostic for Lyme Arthritis   $ 42,115.50
Lynntech Inc Xanapath $ 200,307.09 $ 18,497.25
Lynntech Inc A New Hyperspectral Image Capture Tool for Evaluating TBI   $ 24,156.08
Lynntech, Inc Ultrasensitive, Label-Free Nanowire Biosensing Arrays $ 45,326.78 $ 8,967.86
Lynntech, Inc Novel Nanostructures for Topical Photodynamic Therapy $ 113,909.62 $ 20,417.96
Lynntech, Inc Novel Fluid Management System for Microfluidic Devices $ 188,810.52 $ 55,668.73
Lynntech, Inc. Photodynamic Therapy of Disseminated Peritoneal Tumor Using New Photosensitizers $ 101,600.83 $ 142,878.42
Lynntech, Inc. Compact, Lightweight, Disposable Electrochemical Pump for Portable Drug Infusion with Direct Flow Monitoring $ 44,234.95 $ 871.81
Lynntech, Inc. Portable Cathode-Air-Vapor-Feed Electrochemical Medical Oxygen Concentrator Phase II   $ 82,342.12
Lynntech, Inc. An Integrated Optical DNA Detector for Portable PCR $ 80,654.34 $ 65,854.53
Lynntech, Inc. Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System $ 52,453.51 $ 136,615.77
MacuCLEAR, Inc. Treatment for dry Age Related Macular Degeneration $ 244,479.24  
Marval Biosciences Inc NCTX-140 $ 236,215.14 $ 8,264.11
MDx BioAnalytical Laboratory, Inc. Development of diagnostic tests based on polypeptide biomarker panels $ 44,500.00 $ 199,979.24
med fusion, LLC med fusion clin-labs * clin-trials   $ 244,479.25
Medical Nanotechnologies, Inc Targeted nanotubes for photothermal ablation therapy   $ 63,868.00
Memgen, LLC ISF35 Active Immunogene Therapy for Chronic Lymphocytic Leukemia $ 244,479.25  
MetronomX Nifurtimox for treating neutoblastoma   $ 244,479.25
MicroTransponder, Inc Breaking the Blood Brain Barrier for Treatment of Glioblastoma BBB $ 244,479.24  
MILLAR INSTRUMENTS INC MPVS Cardia PV System $ 244,479.25  
Millar Instruments Inc Mikro-Cath $ 62,068.00 $ 17,571.50
Mirna Therapeutics, Inc. MicroRNA-Based Targeted Therapies for Cancer $ 244,479.25  
Molecular Templates Inc Engineered Toxin Bodies (ETBs), a new class of biologic therapeutics, to treat cancers. $ 90,549.00 $ 153,930.24
Moleculin, LLC Commercialization of p-STAT3 inhibitor $ 52,383.50 $ 192,095.74
Mystic Pharmaceuticals, Inc VersiDoser Drug Delivery Platform $ 244,479.25  
NanoMedical Systems, Inc Development of Molecular Drug Delivery System $ 244,479.24  
NanoRelease Technologies, LLC Nanoparticle and Microparticle Vaccine Delivery Systems $ 75,836.50 $ 77,546.50
Nanospectra Biosciences Inc Multi-Functional Nanotheragnostic for Cancer Identification and Ablation $ 244,479.24  
Neos Therapeutics LP Novel Once Daily Extended Release Therapeutics for ADHD $ 218,184.00 $ 26,295.25
Neuro Resource Group, Inc The development of a Single Patient InterX that will fit into existing Medicare Reimbursement. $ 244,479.24  
Nimbic Systems, Inc Air Barrier System (ABS) $ 98,195.09 $ 146,284.16
Norwell, Inc HER2 Peptide Immunotherapy (GP2) for Breast Cancer in Adjuvant Setting $ 244,479.25  
Nventa Inc HspE7 Therapeutic Vaccine for HPV Diseases $ 43,762.50 $ 200,716.75
Nventa, Inc Poly-ICR:  A Toll-like Receptor agonist adjuvant for vaccine focusing on HPV. $ 43,762.50 $ 200,716.75
Omm Scientific, Inc. Preclinical Development of QseC Antagonists as novel antivirulence therapies for Gram $ 109,905.99 $ 115,000.00
On-X Life Technologies Inc On-X Prosthetic Heart Valve (PROACT) $ 244,479.24  
On-X Life Technologies Inc On-X PreChords Mitral Chordae Repair/Replacement $ 147,251.50 $ 97,227.74
Opexa Therapeutics, Inc Tovaxin therapeutic $ 244,479.24  
Ortho Kinematics Inc Development of the KineGraph Vertebral Motion Analyzer $ 244,479.24  
p53 Inc. Biomarker Directed p53 Tumor Suppressor Therapy of Head and Neck Cancer $ 244,479.25  
PALMAZ SCIENTIFIC INC. Advanced Surface Nanotechnology and Therapeutic Platform for Implantable Biomaterials $ 244,479.25  
Pecan Biotherapeutics Inc Tat Oyi $ 244,479.25  
PHOTO IMMUNE BIOTECHNOLOGY, INC METHODOLOGY FOR DEVELOPMENT PREVENTIVE $ 85,913.00  
PHusis Therapeutics Inc. Development of PDPK1 inhibitor PHT-427 for the treatment of non small cell lung cancer $ 1,500.00 $ 242,979.24
PLx Pharma Inc PL3100, 25 mg GI-safer naproxen capsules $ 244,479.24  
PLx Pharma Inc. PL2200, 325 mg GI-safer aspirin capsules $ 244,479.24  
Protec Maternity Wear, LLC Prevention of Fetal Electromagnetic Field Exposure $ 10,200.00 $ 90,000.00
Pulmotect Inc. Boosting the Innate Immune System of the Lungs $ 71,260.28 $ 117,500.00
RadioMedix, Inc. Metabolic targeting imaging and therapy of cancer $ 123,639.67 $ 120,839.58
Rarecells USA Inc. ISET  Theranostics Project $ 1,322.08 $ 86,524.92
Reata Pharmaceuticals Inc Development of RTA 744 for the treatment of Brain Cancer. $ 244,479.25  
Reata Pharmaceuticals Inc Reata Bardoxolone methyl (Bardoxolone) for Chronic Kidney Disease $ 244,479.25  
Reata Pharmaceuticals Inc. Reata Antioxidant Inflammation Modulators for Central Nervous System Disease $ 244,479.25  
Reata Pharmaceuticals, Inc Reata Antioxidant inflammation Modulators for Cancer $ 244,479.25  
Reata Pharmaceuticals, Inc. Reata Antioxidant Inflammation Modulators for Pulmonary Diseases (Reata AIMs PD) $ 244,479.25  
Receptor Logic, Inc T Cell Receptor mimic (TCRm) $ 244,479.25  
Repair Technologies Inc Activated audit marrow stronal cells (aMSCs) for treatment of immune diseases $ 244,479.24  
REPAIR Technologies Inc. Universal RS-MSC's for Treatment of Ischemic Cardiovascular Disease $ 244,479.24  
Repros Therapeutics Inc Proellex $ 244,479.24  
Resonant Sensors Incorporated Label-free, high throughput screening tool for medical diagnostics and drug discovery $ 43,918.00 $ 144,275.00
Resonant Sensors Incorporated Rapid diagnostic tool for microbial and toxin detection   $ 51,893.23
Resonant Sensors Incorporated Portable photonic sensor system as an early detection tool for ovarian cancer $ 35,467.35 $ 160,355.65
Risk Assessment Laboratories LLC PTD $ 244,479.25  
Rochal Industries LLP Delivery of Antimicrobials for Biofilm Disruption and Prevention $ 28,604.50 $ 91,804.00
Rules Based Medicine Inc Development of molecular diagnostic test for complex diseases $ 244,479.25  
RyMed Technologies, Inc Chlorhexidine Silver $ 110,000.00 $ 110,000.00
Salient Pharmaceuticals Incorporated CASAD COMMERCIALIZATION $ 244,479.25  
Savara, Inc Budesonide for Treatment of Non-Small Cell Lung Cancer $ 244,479.25  
Seno Medical Instruments Inc Imagio Clinical System for Early Detection and Treatment of Cancer. $ 244,479.24  
Smart Imaging Technologies Co. Automated High Volume Screening Technology for Routine IVD tests $ 164,927.00  
Southwest Genetics PA Midgestation Screen for Preterm Birth $ 7,850.00 $ 50,900.00
Spinal Restoration, Inc Biostat System for the relief of chronic discogenic lumbar back pain $ 244,479.24  
Stematix Inc ALLOSTROME $ 244,479.25  
Telehealth Holdings, LLC An Innovative Drug Delivery and Adherence System for Oncology Patients $ 183,757.50 $ 60,721.75
TOMOWAVE LABORATORIES OPTOACOUSTIC BIOSENSOR FOR FAST AND SENSITIVE DETECTION OF PATHOGENS IN BLOOD   $ 119,500.00
TomoWave Laboratories Three-Dimensional Optoacoustic tormography systems for diagnostic imaging of breast cancer   $ 244,479.25
Trinity Laboratories Inc. TLI-1026: A novel multi-modal therapy to treat Fibromyalgia and Diabetic Neuropathy $ 244,479.25  
Trinity Laboratories, Inc. Development of Novel Stable Lipid Nanoparticles of Docetaxel for Treatment of Cancer $ 167,309.78 $ 44,940.51
UroResearch Inc Tissue Bonding Cystostomy {TCB} $ 27,149.50 $ 78,750.00
Vapogenix, Inc Novel, non-opioid localized analgesics $ 119,191.12 $ 125,288.13
VIDACARE CORPORATION OnControl ™ Powered Bone Marrow Aspiration and  Core Biopsy System $ 244,479.25  
Vidacare Corporation EZ-IO® Intraosseous Infusion System $ 104,053.25 $ 140,425.99
ViroXis Corporation Albuterpenoid Product Development Project $ 25,682.50 $ 218,796.74
Wenzel Spine, Inc. VariLift Interbody Fusion System $ 244,479.24  
Womens3D, Inc Womens3D automated ultrasound breast imaging   $ 244,479.24
Xbiotech USA, Inc. MABp2   $ 122,915.52
ZS Pharma, Inc ZS-9 $ 244,479.25  
ZZ Biotech LLC An activated protein C variant therapeutic for stroke and neurological disorders $ 244,479.25  

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Page Last Reviewed or Updated: 26-Mar-2014