If you use part of your home exclusively and regularly for conducting business, you may be able to deduct expenses such as mortgage interest, insurance, utilities, repairs, and depreciation for that area. You need to figure out the percentage of your home devoted to your business activities, utilities, repairs, and depreciation. More Information Home Office Deduction Tax Topic 509 - Business Use of Home Related Forms Form 8829, Expenses for Business Use of Your Home PDF Related Publications Publication 587, Business Use of Your Home (Including Use by Daycare Providers)